Heartwater in Angora goats. I. Immunity subsequent to artificial infection and treatment.
نویسندگان
چکیده
This study confirmed reports that Angora goats are highly susceptible to Cowdria ruminantium and showed that immunization of this breed against heartwater may be difficult hazardous. It was found that if goats were treated on the 2nd or 3rd day of the febrile reaction following the intravenous inoculation of the heartwater agent, few animals survived the infection. If, on the other hand, treatment was instituted on the 1st day of the reaction, the chances of survival were good, but the immunity of the goats to subsequent challenge was poor.
منابع مشابه
Problems encountered in the control of heartwater in Angora goats.
This preliminary investigation confirmed that when Angora goats were immunized against heartwater, either when kids or young goats, they still had an immunity to heartwater a year later when they were challenged with a vaccine containing Cowdria ruminantium. An overwhelming majority of the uninoculated animals which were challenged at the same time were susceptible to clinical heartwater. Strat...
متن کاملSpecific immunity in farm animals to heartwater.
The duration of immunity to heartwater normally varies from 6 months to 4 years. In Angora goats it may be difficult to produce a specific immune response with vaccination. Humoral immunity does not appear to play a role in the development of immunity. It has been suggested that cellular immunity may play a role, but the actual mechanism involved remains obscure. The specific immune response de...
متن کاملHeartwater in Angora goats. II. A pathological study of artificially infected, treated and untreated goats.
Pathological lesions in untreated Angora goats infected with the Ball3 strain of Cowdria ruminantium corresponded with those previously reported. A severe nephrosis was the most prominent pathological lesion in the animals treated after the 1st day of the febrile reaction. Renal ischaemia appears to be central to the pathogenesis of the kidney lesions.
متن کاملDiagnosis of heartwater at post-mortem in ruminants and the confirmation of Cowdria ruminantium in mice.
Criteria that are required to confirm heartwater in ruminants and mice are discussed. In ruminants it entails the macroscopical and microscopical lesions as well as the identification of Cowdria ruminantium in brain smears or histological sections. Macroscopical lesions in the majority of animals that die of the disease include effusion of body cavities, hydropericardium, oedema of the lungs, b...
متن کاملProtective immunity to heartwater (Cowdria ruminantium infection) is acquired after vaccination with in vitro-attenuated rickettsiae.
A Senegalese (S) stock of Cowdria ruminantium was passaged on bovine umbilical endothelial cells with an average interval of 13.9 days (range, 8 to 34 days) between passages. The virulence of infected bovine umbilical endothelial cultures was tested in susceptible goats and sheep by intravenous inoculation of culture supernatant from passages 2 (51 days in vitro), 3 (69 days), 11 (229 days), 14...
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ورودعنوان ژورنال:
- The Onderstepoort journal of veterinary research
دوره 50 2 شماره
صفحات -
تاریخ انتشار 1983